Here’s the critical paragraph you should know- one the Boston U researchers of course would have known about:
But what if? What if this chimeric strain turned out to be more lethal than expected in the human population? What happens if you take an older strain of the virus and swap in the Omicron-level spike; doesn’t that have the potential for trouble? Well, we’ve already seen a “natural experiment” like that, as Florian Krammer points out. There was a strain back in March called XD, which was a Delta that had the Omicron spike protein in it (via recombination). XD did not take off in the human population and did not seem to be more of a problem than the other strains, which is why you’ve probably never heard of it.
In other words, what the Boston U researchers were doing was making a strain that pretty much already existed in nature, and was known not to be able to take off in humans.
It was gain of function. If it “pretty much existed in nature” why did they need to “create it”?
Once again you are focusing on the outcome - which was unknown when they were doing it. It could have easily gone the other way. That’s how ■■■■ happens.
No it was not unknown when they were doing it. They were in effect replicating work that had already been done both in nature and by other organizations.