What percent of public mask wearing is actually effective?

[WuWei]

@Jezcoe

@WuWei

No, it hasn’t.

Yea it has. We know that the chance of infection for the alpha variant was reduced by over 90% with the Pfizer and Modena vaccine.

Even though that chance of infection is affected by the Delta variant… it isn’t reduced to zero.

What metric are you using to determine “infected”?

[Jezcoe]

@WuWei

@Jezcoe

@WuWei

No, it hasn’t.

Yea it has. We know that the chance of infection for the alpha variant was reduced by over 90% with the Pfizer and Modena vaccine.

Even though that chance of infection is affected by the Delta variant… it isn’t reduced to zero.

What metric are you using to determine “infected”?

Getting infected. As in the virus is actively replicating in the body.

We are exposed to infectious pathogens all the time. We aren’t constantly sick because that is how the immune system works.

[WuWei]

@Jezcoe

@WuWei

@Jezcoe

@WuWei

No, it hasn’t.

Yea it has. We know that the chance of infection for the alpha variant was reduced by over 90% with the Pfizer and Modena vaccine.

Even though that chance of infection is affected by the Delta variant… it isn’t reduced to zero.

What metric are you using to determine “infected”?

Getting infected. As in the virus is actively replicating in the body.

We are exposed to infectious pathogens all the time. We aren’t constantly sick because that is how the immune system works.

Does it have to be “actively replicating”?

[Jezcoe]

@WuWei

@Jezcoe

@WuWei

@Jezcoe

@WuWei

No, it hasn’t.

Yea it has. We know that the chance of infection for the alpha variant was reduced by over 90% with the Pfizer and Modena vaccine.

Even though that chance of infection is affected by the Delta variant… it isn’t reduced to zero.

What metric are you using to determine “infected”?

Getting infected. As in the virus is actively replicating in the body.

We are exposed to infectious pathogens all the time. We aren’t constantly sick because that is how the immune system works.

Does it have to be “actively replicating”?

What is this dumb game?

[WuWei]

@Jezcoe

What is this dumb game?

It’s not a game. Your bar for “infected” is wrong. You have no way of measuring it in the asymptomatic.

Do you know why the CDC pushes a Symptom Based Approach rather than Test Based?

[Jezcoe]

@WuWei

It’s not a game. Your bar for “infected” is wrong. You have no way of measuring it in the asymptomatic.

Then the there has to be an assumption that the infection rate among the vaccinated is exactly the same as the unvaccinated and given what we know about the response to the Alpha variant there is absolutely zero indicator that it has been reduced to zero for Delta.

It is not reality based in any way.

[WuWei]

@Jezcoe

@WuWei

It’s not a game. Your bar for “infected” is wrong. You have no way of measuring it in the asymptomatic.

Then the there has to be an assumption that the infection rate among the vaccinated is exactly the same as the unvaccinated and given what we know about the response to the Alpha variant there is absolutely zero indicator that it has been reduced to zero for Delta.

It is not reality based in any way.

Sure, you have to stop making the claim unless you can back it up if you want people to believe.

You don’t know about the Alpha variant, you can’t know.

The asymptomatic are the unknown. I believe the more you vaccinate, the more asymptomatics you will have - the vaccine works for that.

Eventually people will stop taking a test everytime they sneeze. Pretty soon. Especially among the vaccinated.

Just be honest about it. Don’t claim things based on lab studies and extrapolations. Keep it simple. Nothing but the truth.

And every now and then say “We don’t know.”

[Jezcoe]

@WuWei

I believe the more you vaccinate, the more asymptomatics you will have - the vaccine works for that.

That increase is wildly offset by the rate of infection going down.

This cannot be stressed enough… the rate of actually getting infected in the first place goes way down with the unvaccinated.

If exposed to the virus… the vaccinated are much much much less likely to get infected than the unvaccinated and thus much much much less likely to vectors.

It is getting super boring having to repeat this.

So this is the last time.

[WuWei]

@Jezcoe

That increase is wildly offset by the rate of infection going down.

It might, but you hsven’t proven that. Don’t claim things you can’t prove.

[WuWei]

@Jezcoe

there is absolutely zero indicator that it has been reduced to zero for Delta.

What is it?

[WuWei]

I don’t know who she is, but this is a pretty good explanation of what I’m talking about.

Coronavirus: few vaccines prevent infection – here's why that's not a problem

Sarah L Caddy

Clinical Research Fellow in Viral Immunology and Veterinary Surgeon, University of Cambridge

[Jezcoe]

@WuWei

@Jezcoe

That increase is wildly offset by the rate of infection going down.

It might, but you hsven’t proven that. Don’t claim things you can’t prove.

Is the infection rate of the vaccinated equal to that of the unvaccinated?

[Jezcoe]

@WuWei

@Jezcoe

there is absolutely zero indicator that it has been reduced to zero for Delta.

What is it?

60% to 70%

[Jezcoe]

@WuWei

I don’t know who she is, but this is a pretty good explanation of what I’m talking about.

Coronavirus: few vaccines prevent infection – here’s why that’s not a problem

Sarah L Caddy

Clinical Research Fellow in Viral Immunology and Veterinary Surgeon, University of Cambridge

And the CDC says this

https://www.cdc.gov/media/releases/2021/p0329-COVID-19-Vaccines.html

It takes about two weeks following each dose of vaccine for the body to produce antibodies that protect against infection. As a result, people are considered “partially vaccinated” two weeks after their first dose of mRNA vaccine and “fully vaccinated” two weeks after their second dose. These new vaccine effectiveness findings are consistent with those from Phase 3 clinical trials conducted with the vaccines before they received Emergency Use Authorizations from the Food and Drug Administration. Those clinical trials evaluated vaccine efficacy against COVID-19 disease, while this study evaluated vaccine effectiveness against infection, including infections that did not result in symptoms.

Delta has reduced that effectiveness… but not to zero.

If exposed to the virus, the vaccinated are much less likely to get infected than those who are unvaccinated.

[WuWei]

@Jezcoe

@WuWei

@Jezcoe

That increase is wildly offset by the rate of infection going down.

It might, but you hsven’t proven that. Don’t claim things you can’t prove.

Is the infection rate of the vaccinated equal to that of the unvaccinated?

Who knows?

[WuWei]

@Jezcoe

@WuWei

@Jezcoe

there is absolutely zero indicator that it has been reduced to zero for Delta.

What is it?

60% to 70%

Is it? Show your work.

[WuWei]

March 29th.

[WuWei]

@Jezcoe

Delta has reduced that effectiveness… but not to zero.

Ok, prove it.

[Jezcoe]

@WuWei

March 29th.

Is the immune response between Alpha and the Delta variant such that the infection rate is equal to that of the unvaccinated?

The answer is no. No it hasn’t.

The vaccinated are still much less likely to get infected if exposed and with booster shots coming the odds get even better.

[Jezcoe]

@WuWei

@Jezcoe

Delta has reduced that effectiveness… but not to zero.

Ok, prove it.

Effectiveness of COVID-19 Vaccines in Preventing SARS-CoV-2...

During December 14, 2020–August 14, 2021, full vaccination with COVID-19 vaccines was 80% effective in preventing RT-PCR–confirmed SARS-CoV-2 infection among frontline workers, further affirming the highly protective benefit of full vaccination up to and through the most recent summer U.S. COVID-19 pandemic waves. The VE point estimates declined from 91% before predominance of the SARS-CoV-2 Delta variant to 66% since the SARS-CoV-2 Delta variant became predominant at the HEROES-RECOVER cohort study sites; however, this trend should be interpreted with caution because VE might also be declining as time since vaccination increases and because of poor precision in estimates due to limited number of weeks of observation and few infections among participants.

And to not rely on just one study, other studies coming out are putting the reduced chance of infection in the same 60% -70% ballpark.