24 But I hold not my life of any account as dear unto myself, [g]so that I may accomplish my course, and the ministry which I received from the Lord Jesus, to testify the [h]gospel of the grace of God. 25 And now, behold, I know that ye all, among whom I went about preaching the kingdom, shall see my face no more. 26 Wherefore I testify unto you this day, that I am pure from the blood of all men. 27 For I shrank not from declaring unto you the whole counsel of God. 28 Take heed unto yourselves, and to all the flock, in which the Holy Spirit hath made you [i]bishops, to feed the church of [j]the Lord which he [k]purchased with his own blood. 29 I know that after my departing grievous wolves shall enter in among you, not sparing the flock; 30 and from among your own selves shall men arise, speaking perverse things, to draw away the disciples after them.

IMO Paul is saying that his mortal life is not important compared to his life in Christ. He showed all those who witnessed his ministry that he did not back down from threats, trials or beatings. He continued on in the work of our Lord. Now he is leaving them and going to Jerusalem and he’s warning them of the trials that will lie ahead when he leaves and to understand that they’ve given their life to Christ. Continue on in The Lord’s work and know that many evil forces are coming to work against them but be strong.